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Some patients may be trained to manage their own injections at home, but this should only be done with proper instruction and supervision

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All organisms use either the NADPH-dependent TrxR- or Gsr-driven systems, or both, to provide reducing power to RNR [35]

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Isolation of polar metabolites For the metabolomics of tissues, 100200 mg of weighed tissue was homogenized in 1 ml of ice-cold 80% methanol with a QIAGEN Tissue Lyser II (three sets of 2 min on maximum speed, with 2 min of rest on dry ice in between sets)

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