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Description
In some embodiments, the otic formulation or composition comprises between about 0.01% to about 20% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof
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and 4hypertonic flexor and extensor muscles, clonus and hyperreflexia, the latter including a positive curling reaction

Comparative metabolism of 1,2,3,3,3-pentafluoropropene in male and female mouse, rat, dog, and human liver microsomes and cytosol and male rat hepatocytes via oxidative dehalogenation and glutathione S-conjugation pathways

This will give us a final concentration of 2.5mg/ml (or 2500mcg/ml)

Total consumption of each fluid was recorded, and sucrose preference was calculated as the average sucrose consumption ratio from the first and second hours
