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Overall, the present analysis suggests that in OI, benefits of the 300-mg maintenance dose (improvement in opioid abstinence, treatment retention, and reduced opioid withdrawal) outweigh the risk of adverse events

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Dose: Horses: 0.02-0.05 ml/kg, Foals: 0.033-0.056 ml/kg, Cattle: 0.02-0.05 ml/kg, Calves: 0.033-0.056 ml/kg, Dogs: 0.025-0.25 ml/kg, Cats: 0.1-0.5 ml/kg