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Rosiglitazone was found to activate eNOS by stimulating heat shock protein (HSP)-90eNOS interaction, with a subsequent eNOS phosphorylation at Ser 1177 (Polikandriotis et al., 2005)

Our design enabled us to test our pre-specified primary and secondary endpoints, which were met: effects of ketamine across dose conditions on (1) emotional task-evoked brain activity, and (2) sub-components of dissociation and other ASCs

The study consisted of 2 sequential phases

"The pathobiology of diabetic complications: A unifying mechanism"

Clinical Toxicology , 47 (2), 101111

Neuropathic pain-induced enhancement of spontaneous and pain-evoked neuronal activity in the periaqueductal gray that is attenuated by gabapentin