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Aerobic or anaerobic cultures of strains AD29 (WT), AD61 ( trx1 ), and AD36 ( tpx1 ) carrying an integrative sty1 promoter-driven HA-oxyR gene were treated or not with the indicated concentrations of H 2 O 2 for the times indicated

These antioxidant systems are insufficient to cope with oxidant stress, ultimately resulting in the irreversible oxidation of functional enzymes and structural proteins, such as band 3, ankyrin and spectrin [141,149], with consequent alteration of the membrane band 3 interactome [59]

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Aggarwal, S., Ghilardi, N., Xie, M

doi: 10.1634/theoncologist.2009-0178 231 YasutakaOMaikoYYoshinoriKYukihikoSShiroO
