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NIVs polypharmacology strategy repurposes approved drugs via the FDAs 505(b)(2) pathway, leveraging existing safety data to reduce time, cost, and development risk

Trends in Molecular Medicine, 11(9), 421-429
Mental fatigue: A clinical study in healthy participants explored the cognitive benefits of a 16mcg/kg intranasal Semax dose after an 8-hour work shift

doi: 10.1016/j.bmc.2013.01.049
Peptide therapy typically requires a loading period of 3-6 months for the full effects to become noticeable

Guo et al, 2009)
