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Recent studies have shown that GSTA4 can reduce cisplatin-induced ototoxicity (23)

Moreover, using rosiglitazone or ACSL4 Small interfering RNA (siRNA) can suppress ACSL4 expression, downregulate the Mfn2/IRE1 pathway, and reduce the levels of 5-hydroxy eicosatetraenoic acid, thereby significantly alleviating ferroptosis and NASH [195]

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