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We observed a DNA-induced conformational change of PrfA by comparing the structures of PrfA in free and DNA bound states (Figs

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A second binding cavity, the H-site, is formed by three regions of the primary structure: 1) in the N-terminus contributions from residues 10,12 and the methylene groups of Arg13, Gly14, and Arg15

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Do not freeze the reconstituted solution freezing damages the peptide structure

For encounters that involve the management of pain medications, it is important that documentation for each of these visits clearly spells out the progress the patient is making in setting goals for pain management