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10.1038/s41380-020-0793-6 70 MairD.ParisA.ZaloumS
The stability and reusability of immobilized CRL (Fe 3 O 4 -CS-DAC-SDS-CRL) were significantly improved simultaneously
[122] Semaglutide was selected as the lead candidate due to its balanced profile of prolonged exposure, full metabolic stability against DPP-4 and neutral endopeptidase, and robust efficacy in sustaining insulin secretion and appetite suppression across species, paving the way for phase 1 trials
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