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A randomized study demonstrated that the use of high-concentration oxygen therapy led to a clinically significant increase in transcutaneous carbon dioxide (PtCO 2 ) levels in patients experiencing severe asthma exacerbations

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Clinical studies specifically monitoring glucose metabolism through oral glucose tolerance tests found no significant changes in glucose handling, and fasting insulin levels remained stable throughout treatment periods lasting up to 24 weeks

Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson's disease

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