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Promising, but still unproven at the clinical level

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Clinical and genetic predictors of paclitaxel neurotoxicity based on patient- versus clinician-reported incidence and severity of neurotoxicity in the ICON7 trial

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10.1007/s12011-019-01821-4

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Another set of related molecules that play a major role in the bioavailability of the IGFs are IGFBPs (Figure 2)

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[PUBMED Abstract] Irving J, Matheson E, Minto L, et al.: Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition

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