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The H3K36me2 modification, which interferes with transcription initiation, acts as a binding site for the chromodomain of the RPD3S histone deacetylase complex

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Whether some of the effects on aging could be attributed to phenomena akin to mitohormesis (Ristow, 2014) could not be discussed because of space constraints

RNS , reactive nitrogen species

doi:10.1001/jama.2023.26074 2
