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If the breakdown process overtakes the rebuilding one, density and bone strength reduce

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Symptoms following acute NSAID overdose are usually limited to lethargy, drowsiness, nausea, vomiting and epigastric pain, gastrointestinal bleeding can occur but very rarely, hypertension, acute renal failure, respiratory depression and coma

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The technique is learnable, but the decisions around it (do you actually need it, what dose, how often, and is something else being missed) are medical judgements, and getting them wrong carries real cost
