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[DOI] [PubMed] [Google Scholar] 32.Menchini-Fabris G.F., Canale D., Izzo P.L., Olivieri L., Bartelloni M
464 Systemic and pulmonary hypertension are the main clinical causes of heart enlargement, cardiac fibrosis, and eventually heart failure

The causes underlying these effects remain unclear, though it is interesting to note that several enzymes involved in synthesis or metabolism of some of these amino acids are among those that have been identified as potential TRX targets through redox protemics approaches (Montrichard et al., 2009)

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Addressing these bottlenecks will extend polymer platforms from hepatic to systemic pathologies

For those with autoimmune conditions, extra caution is warranted
