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They can be unsafe for humans, unsafe in the amounts youre taking, or unsafe for you even if your friend got great results, he says

Four hundred and sixty-two specimens representing 133 morphospecies were identified

This study demonstrated that CD-based polyrotaxanes can provide a transformative solution to drug delivery challenges, achieving controlled and targeted drug release with enhanced therapeutic efficacy

[,] In cases of lead poisoning, the administration of TRF is thought to be able to deactivate generated ROSs through the elimination of free radical chain reactions, thereby inhibiting further production of ROSs and lipid peroxidation by maintaining a sustained redox balance

It falls under the category S0 (Unapproved Substances)

Functions of jasmonic acid in plant regulation and response to abiotic stress