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Description
Antioxidants Redox Signal
The main goal is to bypass the gut
Therefore, studies about chemical induction of hepatocytes from fibroblasts have thrived in the field (Tables 1, 2)
Compared to Supersomes, human S9 and hepatocyte-based assays showed slightly improved metabolite coverage with human liver microsomes providing the closest representation of human in vivo amide hydrolysis (differing from in vivo metabolism in the cases of acetanilide, paracetamol and lidocaine)
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