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SzuliskaMStepieMKregielska-NaronaMSuliburskaJSkrypnikDBak-SosnowskaMet al

In studies of GPX5 knockout mice, we deduced that GPX5 is a way to maintain the integrity of sperm DNA function by removing excess H 2 O 2 , and these mice did not exhibit significant defects in the epididymis and sperm cells ( 2 O 2 scavengers was detected (Noblanc et al., 2012), proving that after SNGPX4 and GPX5 double knockouts, the epididymal tissues of mice produced oxidative stress responses, indicating that SNGPX4 and GPX5 play a role in maintaining the normal structure of the sperm nucleus in the epididymal tissue (Noblanc et al., 2012)

Br J Pharmacol 158(4):936946 Pike JW, Meyer MB, Bishop KA (2012) Regulation of target gene expression by the vitamin D receptor-an update on mechanisms

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doi: 10.1016/0006-291x(85)91687-0

Lutein and zeaxanthin supplementation also failed but only among those getting enough in their diet
