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Biomed &Pharmacotherapy

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Glutathione is a dietary supplement

The expression of glial fibrillary acidic proteina marker of activated astrocytesdecreases, enhancing astrocyte glial cell activity (Jiao et al., 2021)

The supply of NADPH is essential to regenerate GSH and dictates the rate of H 2 O 2 reduction by Gpx while keeping the reduced status of mitochondria

By synthesizing data from clinical trials and reviews, we categorized the most clinically relevant supplements according to their primary effectsglycemic control, lipid regulation, oxidative stress reduction, and hormonal balancewhile also detailing their recommended doses and treatment durations