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In addition, puzzle dipeptides can promote the synthesis and release of neurotransmitters, improving the efficiency of nerve conduction
Uofmhealth.org
Here is the honest evidence status up front, because it shapes everything that follows: the human data on this combination is essentially non-existent
The open-label design of REDEFINE 4 is worth noting
For individuals with BMI above 30 or BMI above 27 with comorbidities, FDA-approved GLP-1 receptor agonists (semaglutide, tirzepatide) have far stronger evidence and produce dramatically greater weight loss
doi: 10.1128/AAC.05879-11 99 LiuJ.MahmoodM
