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Among them, p38 MAPK not only represents the most extensively characterized isoform but is also regarded as a highly promising therapeutic target due to its central role in inflammatory and stress responses

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Changes in instrumental conditions such as inlet interface contamination, ionization efficiency, mobile phase composition or column performance, introduce a systematic bias in the instrumental response, and can also reduce its precision

Vernet P, Fulton N, Wallace C, Aitken RJ: Analysis of reactive oxygen species generating systems in rat epididymal spermatozoa