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From November 1, 2023 to April 1, 2024 (24 weeks in total), participants received training subjects for three times a week, namely 4:40 5:30 pm on every Monday, Wednesday and Friday

Interestingly, one of the newly introduced cysteine residues (Cys-207) apparently forms an intermolecular disulfide bridge in the crystal (Supplementary Figure S2), which may promote crystallization

Overall, the multifaceted role of GPX4 makes it an intriguing focal point for therapeutic interventions and demonstrates its potential to shape the future of cancer therapy

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