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A double-blind, placebo-controlled trial in 95 patients with irritable bowel syndrome or inflammatory bowel disease and normal B12 levels found no significant improvements in fatigue, although B12 levels increased in the B12 group who received 1000 g per day per os (p.o.) for 8 weeks (form not reported)

At neomycin concentrations of 100, 200, and 400 M either inhibitor demonstrated partial attenuation of Dihexa otoprotection, indicating at least partial reliance on their associated signaling proteins for protective effects (Figure 6A)

doi: 10.1159/000337155