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In this context, ferroptosis represents a promising alternative to overcome therapy resistance in cancer, as its induction can suppress tumor growth, improve immunotherapy responses, and offer a new strategy to attack cancer through regulated lipid peroxidation [19]

[DOI] [PMC free article] [PubMed] [Google Scholar] 137.Feldman EL et al

Antioxidant and cardioprotective activity of Tinospora cordifolia (Willd.) Miers ex Hook

Significantly, metformin has been demonstrated to normalize pulsatile GnRH secretion by reducing circulating insulin levels

Of course, it is more complicated, with other cofactors involved, but that is the foundation

[DOI] [PMC free article] [PubMed] [Google Scholar] 270.Schjoldager, K