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TB-500 is primarily known for its ability to bind to actin, influencing cell motility and shape

Li S, Wang Y, Zhang X, Xiong X, Zhou F, Li X, Fan J, Liang X, Li G, Peng Y, Li Y

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Int J Mol Sci (2023) 24:3817

In addition, GLPs suppress both the upregulated expression of the (pro)renin receptor (PRR) and its cleaved soluble variant (sPRR), leading to diminished urinary renin activity and reduced angiotensin II (Ang II) concentrationsultimately preventing pathological overactivation of the renin-angiotensin system (RAS)