isoniazid glutathione Mitochondrial injury and depletion in HepG2 cells treated and quality Isoniazid (PIM 288)
Description
There is evidence to suggest that PPA are formed in healthy individuals at therapeutic doses, particularly following repeated doses, suggesting that not all NAPQI is scavenged by glutathione even during therapeutic administration (see Fig
[PubMed 3748340] 2133
10.1038/ng.2586 Nat
PMID 19549913
Nature 536 , 446450 (2016)
J.LaoF.FuP
