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Alternatively, malate can enter the TCA cycle as a molecule with four carbon atoms, including asparagine alanine-serine cysteine-preferring transporter 2 (ASCT2) substrates (Scalise et al., 2018)

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8.2 Ferroptosis exacerbates central inflammation Neuroinflammation is primarily initiated by astrocytes and microglia in response to factors such as injury, infection, exposure to toxins, or autoimmune reactions

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