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While the concern is worth observing, it does not seem to be scientifically proven

These components activate pattern recognition receptors (PRRs), including TLRs and NLRs, on immune cells

And I think that this is just really exciting, the research that has gone into beta-glucan and the potential

In preclinical research, doses from 6 g/kg to 20 mg/kg caused no acute organ toxicity, and thorough mutagenicity, genotoxicity, and teratogenicity assays returned negative results

Protects the skin from irritation with weak acidity close to healthy skin pH

Similarly, Propionibacterium acnes has also been proposed as an etiologic agent given the higher frequency of genetic material found in sarcoidosis granulomas compared to controls, as well as similar exaggerated immune response to Priopionibacteria in sarcoidosis T cells compared to normals (7)