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Supportive skincare should focus on: Barrier repair Hydration Minimal irritation Avoidance of harsh exfoliants Over-treatment frequently worsens sensitivity

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10.1142/S0192415X13500870 25 GuytonK

Known as the sunshine vitamin, Many people are deficient due to limited sun exposure, dietary gaps, or lifestyle factors, which can lead to fatigue, low immunity, and weakened bones

They were able to replicate the negative correlation in murine models where miR-338-5p knockdown increased IL-6 expression [74]