glutathione crohns disease Intestinal amino acid metabolic response and its roles in inflammatory bowel | Cell Communication and Signaling Drug delivery strategies in the
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10.1111/j.1471-4159.2005.03023.x 98 WaniR.MurrayB
In glutamatergic neurons, ferroptosis-driven GPX4 dysfunction and mitochondrial collapse amplify excitotoxicity, while astrocytes lose their ability to regulate glutamate or maintain the bloodbrain barrier (BBB), exacerbating edema (Jacquemyn et al., 2024
A systematic review (PMID: 40756949) examined its emerging use in orthopaedic sports medicine, while a 2025 pilot study (PMID: 40131143) provided early human safety data
Inflammopharmacology 31:19291949
Rather than stimulating metabolism directly, it alters upstream behavioral drivers of energy consumption
doi: 10.3945/an.117.016329 87
