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Taken together, c-Met could be targeted using selective and non-selective inhibitors, monoclonal or bispecific antibodies, and miRNAs to inhibit tumor progression

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As all these dendritic and spine phenotypes have been observed both by exposing the animal to a stressful situation or by administering corticosterone, it is evident that the stress hormone plays a major role in dendrite and spine remodeling

In addition, daratumumab has been conjugated to DOTA for radiolabeling with the alpha-emitter actinium-225 ( 225 Ac), showing potent CD38-positive tumor cell-killing in vitro and enhanced anti-tumor activity (~ 30-fold) in vivo without significant side effects [131]

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Regular B12 supplementation is necessary to maintain optimal levels and prevent deficiency from occurring again