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2020 doi: 10.1016/j.jpainsymman.2020.10.031
The poor responses to the conventional therapy are leading to a development of new immunotherapy procedures including intralesional adenoviral vector-mediated transfer of CD40L, a tumor necrosis factor gene [21], therapy with a plasmid DNA encoding staphylococcal enterotoxin B [22], and systemic tratment with liposome-encapsulated muramyl tripeptide [23]
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