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Reconstitution rapporte dans les protocoles d'tude titre purement informatif sur les protocoles d'tude publis, la reconstitution dcrite dans la littrature de recherche est la suivante : Matriel utilis : fiole de 10 mg + eau bactriostatique 2 mL + seringue U-100 2 mL d'eau bactriostatique taient prlevs Le diluant tait introduit lentement dans la fiole, le long de la paroi La fiole tait roule doucement (sans agitation) Concentration obtenue : 5 mg/mL (5 000 mcg/mL) 250 mcg = 5 units, 500 mcg = 10 units La calculatrice de dosage permet de retrouver le volume correspondant aux concentrations rapportes dans la littrature

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A significant improvement in health was reported in three patients with mitochondrial disease connected with respiratory chain IIIV who were treated with 50 mg/kg/day with L-carnitine and complex vitamins of the B group, coenzyme Q10, and folic acid [130]

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