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While heterogeneity exists among the population characteristics and study techniques, most studies show that both diversity and richness of the microbiome are lower in breastfed than formula fed infants, with higher levels of Proteobacteria and Bifidobacteria, and lower levels Bacteroidetes and Firmicutes found in breast fed infants compared to those who are formula fed 34, 35

Absorption of the IFB12 complex mainly takes place through receptor sites in the terminal ileum, at an alkaline pH, and in the presence of calcium ions (Allen et al., 2018

doi: 10.1097/01.DSS.0000452629.76339.2b

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