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2023 , e202304 (2023)

Importantly, perianal fistulas serve as the initial symptom complex of CD in approximately 10% of patients, often leading to substantial delays in definitive diagnosis 8,9

NAC may prevent ferroptosis by activating Nrf2, which regulates the expression of metallothioneins, ferritins and ferroportins, thereby preventing iron accumulation

16 In the context of cancer, dysregulation of copper metabolism exerts a dual effect on tumor progression

doi:10.2147/dddt.S471525

10.1073/pnas.72.5.1858 Proc
