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Tumor cells take up glucose through glucose transporters (GLUTs) and convert it to glucose-6-phosphate(G-6-P) via hexokinase 2 (HK2)

The timidity which seemed to have abated the fire of the Whigs, when the first intimations of the invasion were given by the Canada spy and the Oneida sachem, now disappeared, when the threatened danger was at their doors, and the call of Herkimer was responded to with alacrity, not only by the militia, but most of the members of the Tryon county committee entered the field as officers or volunteers

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Pope 2000:5580), and this also may have slowed adoption of the technology