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The former predominantly releases interferon- (IFN-) and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are less relevant to CRS pathogenesis, compared to interleukins (IL-6, IL-8, IL-10, IL-1a), tumor necrosis factor- (TNF-) and monocyte chemoattractant protein-1 (MCP-1), among others, which are released by CAR-T cells

FDA approves 100th monoclonal antibody product

This chart shows clinical trial protocols, not a prescription

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How quickly does FTPP work In primate studies, metabolic improvements appeared as early as day 3