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Mammalian studies have shown that these metabolites include SCFAs, secondary bile acids (BAs), vitamins, gases, tryptophan and indole derivatives, and neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA) (reviewed by Liu et al., 2022a)
Long-term safety depends on baseline health status, biomarker monitoring, and individual tolerance
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Tumor Biol (2014) 35:107739
Additionally, UMB upregulated SIRT1 and PPAR signaling pathways, mitigating oxidative injury and inflammation [568]
