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Inflammation or injury to either can cause sharp pain, stiffness, and difficulty bending the leg

However, both peptides were effective, and the difference was not large

Using Youdens Index, which locates the threshold value that maximizes the distance between the ROC curve and the line of chance, to identify optimally performing threshold values from each ROC curve resulted in 85.87% sensitivity to detect PROMIS depression T-scores within the severe range based on the adjusted model, but with specificity of 34.05%

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