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The mechanism by which probiotics exert their positive effects is still not known but it is though that they might influence neuroactive metabolites like gamma-aminobutyric acid and serotonin (Israelyan and Margolis, 2018)

In this study, it appears that L-carnitine has a significant effect in improving frailty status in general, and hand grip test and exhaustion in particular

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These findings provided the closest available in vivo molecular signature for brain IR in depression and showed important sex differences in these pathways

Oct 10 2023;81(11):1447-1461