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Five-year survival rates are below 12%, even with the most aggressive trimodal therapies

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The researchers utilized standardized scoring systems to quantify cartilage damage, assessing factors including surface irregularity, structural disorganization, and cellular changes

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Q3: How did a 10mg dose compare to other parameters in the literature

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The only evidence around B12 shows that vitamin B12 benefits us by: making red blood cells keeping the nervous system healthy releasing energy from food working together with folate (vitamin B9)

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While both compounds work through different mechanisms that theoretically could complement each other, the safety, efficacy, and optimal dosing of this combination remain completely unknown

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