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Enhanced Mood and Mental Clarity: B12 supports brain health, which can improve mood, cognitive function, and mental clarity

Dr Andrew Thornber, chief medical of Now Patient told Express.co.uk its rare to overdose on vitamin B12, but it can occur if too much has been taken

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Retatrutide is still investigational and not approved by any regulator as of April 2026, so everything below is presented as clinical-trial data, not as medical guidance
A sufficient supply of B12 is therefore the first step in optimising the methylation processes
