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Proc Amer Radium Soc, 2004

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Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice

Linkova NS, et al

GABAergic deficits and glutamate excitotoxicity are two essential signaling pathways that could be addressed to treat autism, thus medications targeting these pathways are critical for treating behavioral symptoms

This was described[13-17] in the treatment of deep vein thrombosis and colitis ischemia/reperfusion, duodenal venous congestion and cecum perforation[13-16], and bile duct ligation-induced liver cirrhosis and portal hypertension rat injuries[17]