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Local and systemic peptide therapies for soft tissue regeneration: a narrative review Summary: This review identified various peptides, including those related to TB500, demonstrating efficacy in soft tissue repair

It is also important not to keep repeating injections to often as to do so can lead to tissue damage, particularly in the case of subacromial injections

Proponents argue this maintains more stable tissue levels, though others find once-daily dosing equally effective with better compliance

[DOI] [PMC free article] [PubMed] [Google Scholar] 6

The effects of ANP on lipolysis are more relevant to primates than rodents, as rodents express over 100 times the level of the clearance receptor NP clearance receptor (NPCR), which mitigates the effect of ANP on lipolysis (112, 113)
