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Am J Physiol Gastrointest Liver Physiol 294:G208-216

Sleep-enhancing peptides exert systemic effects by acting on circadian regulators (e.g., CLOCK, BMAL1), restoring pineal-mitochondrial signaling, and enhancing endogenous GH release (Table 3)

Data analysis: Calculate the expiration date under normal storage conditions through chemical kinetics models (such as the Q10 rule)

When MSTN bind its receptors ALK5 and ActRIIB, Smad 2/3 gets involved in promoting the proliferation of fibroblasts, their differentiation into myofibroblasts, and expression of ECM proteins, thus contributing to fibrogenesis [59]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Marella M., Chabry J