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Description
When melanin gathers in certain areas, it forms spots such as freckles, sun spots, or other marks

Skin changes include focal fibrosis within papillary dermis, pigmentary incontinence and lymphohistiocytic infiltrate
[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Labonia WD, Morelli OH, Jr, Gimenez MI, Freuler PV, Morelli OH
The connection between the dynamic remodeling of the mitochondrial network and the regulation of muscle mass

doi: 10.1177/1533317508325093

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