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The common systemic features reported were fatigue, glossitis, weight loss and anorexia that was found in 34%, 31%, 27% and 22% of cases respectively.[4] Hyper pigmentation of skin has been reported only rarely as the presenting manifestation of vitamin B12 deficiency as found in this patient.[5] There are only two such Indian reports found in Indian literature.[6,7] After the treatment, hematologic response begins after several days and, moreover, the final hematologic landmark is the blood count, including mean corpuscular volume (MCV) that should be completely normal by the eighth week.[8] The cutaneous manifestation of vitamin B12 deficiency is skin hyper pigmentation, vitiligo, hair changes, and recurrent angular stomatitis

Glossary 2OG, 2-oxoglutarate

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If they were to check their lab tests they would also see corresponding changes to thyroid lab tests including: Changes in the TSH level (usually an increase) An increase in thyroid antibodies An increase in ESR and CRP (inflammatory markers) While this may sound scary or concerning you should be aware that the symptoms fade relatively quickly once the iodine is stopped and the chance of any long-term harm is essentially non-existent