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Within the pyrimidine metabolism pathway, concentrations of UMP and cytidine decreased, while levels of dihydrouracil and uracil increased (Figure 4B)

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However, individual differences and other factors like existing health conditions also play a role

However, in the early 21 st century it became possible to extend the understanding of decades of cumulative seminal research by employing a systems pathogenesis framework to define the multiple interacting elements and processes contributing to the development of colonic inflammation

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