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These are rare at the doses used in supervised clinical care and when they occur, they're typically mild and transient

published effects are primarily preclinical and exploratory

24 A study in 2008 showed that increasing B12 levels through i.m

But if your diet isnt optimal, or if your body has an underlying issue, it may not absorb enough B12 which can lead to health problems

"Stimulation of the growth hormone (GH)-insulin-like growth factor I axis by daily oral administration of a GH secretogogue (MK-677) in healthy elderly subjects." The Journal of Clinical Endocrinology & Metabolism 81.12 (1996): 4249-4257

Side Effect of High-Dose B-12 September 06, 2024 Vitamin B-12 section of our B Vitamin Supplements Review, which includes our Top Picks among B vitamins