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Additionally, activated caspase-1 cleaves GSDMD and releases its N-terminal domain, which is translocated to the cell membrane, where it forms pores to induce pyroptosis and then mediates the release of cellular contents such as IL-1 and IL-18 (Fig

Influence of visible light on cutaneous hyperchromias: clinical efficacy of broad-spectrum sunscreens

Zwang Y

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Single agent, canfosfamide (C, TLK286) vs pegylated liposomal doxorubicin (D) or topotecan (T) in 3rd-line treatment of platinum (P) refractory or resistant ovarian cancer (OC): phase 3 study results [Abstract]