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Opiate antagonist naloxone is reduced in liver to naloxol

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Using l-tyrosine and l-3,4-dihydroxyphenylalanine as substrates, the extract exhibited inhibitory effects on tyrosinase activity similar to those of arbutin and vitamin C, in a concentration-dependent manner

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doi: 10.1089/ars.2010.3215

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To test whether the observed reduction in PhoA activity is dependent on glutathione levels in the periplasm, we also measured PhoA activity in a cydD mutant

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Laitinen, L

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they're foundational

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